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1 Introduction Melasma is a common hyperpigmentation disorder, especially in the female gender, that is usually presented symmetrically as light brown to dark brown hyperpigmented spots in the face and also it can be exacerbated through prolonged sun exposure (Noh et al., 2014)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 252.Ghezzi P